一個較實用的合成醛的方法，反應一般在室溫下進行，反應時間較短，可氧化大部分伯醇、烯丙醇和芐醇，而且產率較高，副反應較少。一般仲醇很難反應，可能會生成亞硝酸酯。

反應示例

A typical procedure for oxidation of 4-nitrobenzylalcohol: a mixture of NaNO₂(1035 mg, 15mmol) and 4-nitrobenzyl alcohol (5 mmol) in acetic anhydride (2 mmol) was stirred.  A spontaneous exothermic reaction took place which was controlled by cooling the mixture in ice.  After completion of the reaction (TLC), the product was extracted with ether (2 × 10 ml).  Removal of the solvent under reduced pressurea.orded crude 4-nitrobenzaldehyde which was further puri.ed by column chromatography(petroleum ether–ethyl acetate, 9 : 1).

Reference:  J. Chem. Soc., Perkin Trans. 1, 2000, 3559–3560