利用Mn(III)salen催化劑催化下氧化(Z)烯烴不對稱合成環氧化物的反應。
反應機理
首先氧化Mn(III)-salen絡合物得到Mn(v)活性中間體，反應的對映選擇性可以由Jacobsen提出的烯烴從催化劑的頂端進行反應 或Katsuki提出的從側上方進行反應來解釋。
有三種可能的反應機理：
反應實例
參考文獻
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編譯自：Name Reactions （A Collection of Detailed Reaction Mechanisms）, Jie Jack Li, Jacobsen–Katsuki epoxidation，page 329-330.
